Performance Comparison of Two LabChip Microfluidic Platforms for Protein, DNA and RNA Analysis

February 16, 2011 at 5:00 pm Leave a comment

The analysis of any mixture,including complex biological material, includes its separation into single components and an assessment of their quantities in the sample. However, the sample complexity in these materials necessitates the combination of a highly sensitive detection method with an efficient separation method. The development of electrophoretic microchip platforms in the 1990s has allowed these separations to take place on smaller scales and i n shorter times than traditional slab gel electrophoresis techniques. Automated electrophoresis systems have decreased sample run times to the order of hundreds of seconds and parallel processing may be performed.

The technical note below, describes the performance of a variety of assays available with the Experion automated electrophoresis system from Bio-Rad Laboratories. The technical note compares the performance of the Experion assays to the performance of the assays of another microfluidics system, the 2100 Bioanalyzer from Agilent Technologises. The assays were analyzed in terms of accuracy, reproducibility, and sensitivity for both systems.

To see an illustration of the Experion in use and a to get an idea of how it fits into a typical molecular biology workflow, download the Closing the Next Generation Gap poster from the Baylor College of Medicine’s Microarray Core Facility.

Performance Comparison of Two LabChip Microfluidic Platforms for Protein, DNA and RNA Analysis

Entry filed under: Bio-Rad Product Highlight, Bio-Rad Tech Note, Experion. Tags: , , , , .

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