New link in the DNA repair process of cells

June 19, 2013 at 2:36 pm Leave a comment

Dan%20Durocher_webThe body’s ability to detect and repair DNA errors that can occur during normal cell processes is essential to healthy human development. A new discovery by researchers at Mount Sinai’s Samuel Lunenfeld Research Institute released today in the prestigious journal Nature, uncovers a previously unknown link in the DNA repair process, offering a deeper understanding of how DNA repair mechanisms fail in diseases like cancer.

Senior Investigator Dr. Daniel Durocher and his team of researchers at the Lunenfeld, including lead author Dr. Amelie Fradet-Turcotte, have discovered the function of a protein that is vital to the efficient repair of DNA damage. This protein, called 53BP1, responds to a unique ‘flare’ signal called ubiquitin (another protein involved in cellular regulation), when there is DNA damage present and then works together to accelerate the repair process.

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Entry filed under: Biotechnology News and Info from Canadian Universities. Tags: .

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