Posts tagged ‘stem cell research’
For people at risk of the devastating ulcers and gangrene associated with type 2 diabetes, stem cell therapy could offer some hope for a new, effective therapy, according to research just published from Mount Sinai Hospital.
In the study, damaged muscle and blood vessels in mice with peripheral vascular disease showed “substantial” rapid healing after the injection of human umbilical cord blood stem cells. The research was lead by Associate Scientist Dr. Ian Rogers (photo) of the Lunenfeld-Tanenbaum Research Institute at Mount Sinai. It was published online (January 18, 2014) in Stem Cell Review and Report.
Stem cell scientists have moved one step closer to producing blood-forming stem cells in a Petri dish by identifying a key regulator controlling their formation in the early embryo, shows research published online today in Cell.
The work was reported by Dr. Gordon Keller, Director of the McEwen Centre for Regenerative Medicine, and Senior Scientist at Princess Margaret Cancer Centre, both at University Health Network. Dr. Keller is also Professor in the Department of Medical Biophysics at the University of Toronto and holds a Canada Research Chair in stem cell biology.
Using mouse models to study the process of blood cell development, Dr. Keller and his team demonstrated that the retinoic acid signalling pathway is required for formation of blood-forming stem cells. Retinoic acid is produced from vitamin A and is essential for many areas of human growth and development.
Click here for the Canadian Asset Map for Stem Cell and Regenerative Medicine: Executive Summary
It’s a discovery that could lead to new therapies for people with brain injuries or neurodegenerative diseases: a common diabetes drug can help turn brain stem cells into nerve cells.
The study, led by Dr. Freda Miller, Professor in the Department of Molecular Genetics at the University of Toronto and Senior Scientist at The Hospital for Sick Children (SickKids) is published in the July 5 advance online edition of Cell Stem Cell.