Did you think that sample prep and primer design was straight forward? What impact can the use of different housekeeping genes as controls have on your results? You will be shocked at what you find out.
In this video, Sean Taylor of Bio-Rad Laboratories explains exactly what you must know to perform RT-qPCR according to MIQE standards.
People who carry a high-risk gene for Alzheimer’s disease show changes in their brains beginning in childhood, decades before the illness appears, new research from the Centre for Addiction and Mental Health (CAMH) suggests.
The gene, called SORL1, is one of a number of genes linked to an increased risk of late-onset Alzheimer’s disease, the most common form of the illness. SORL1 carries the gene code for the sortilin-like receptor, which is involved in recycling some molecules in the brain before they develop into beta-amyloid a toxic Alzheimer protein. SORL1 is also involved in lipid metabolism, putting it at the heart of the vascular risk pathway for Alzheimer’s disease as well.
Bio-Rad Laboratories, Canada is having an incredible, limited-time, end-of-year sale. You can save up to 60% on items such as:
- Protein Standards
- Reverse Transcription Reagents
- Mini-PROTEAN Tetra Systems
- Blotting Systems
- Power Supplies
and much, much more…
For details see the Bio-Rad Laboratories, Canada End of Year sale page and start saving!
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Bio-Rad Laboratories, Inc. today announced the launch of its CFX Manager software version 3.1. The software allows users to quickly and easily set up a real-time PCR experiment, assess data quality, and interpret results.
Bio-Rad’s CFX Manager software is compatible with all CFX platforms and features optimized run files for Bio-Rad’s wet-lab validated PrimePCR™ primer and probe assays, saving researchers time and money.
The updated CFX Manager software includes new features for allelic discrimination, including automatic genotype call assignments based on a proprietary clustering algorithm, the option to change calls directly in the allelic discrimination chart, and a feature that allows users to view a map of the calls directly on the plate view.
Version 3.1 also includes an improved CFX qualification plate workflow that enables researchers to verify the performance of the CFX real-time PCR system with just a few clicks. A PDF report with pass/fail results for each criterion is automatically generated after the experiment to help users assess their instrument’s performance.
For users that require mandatory login and audit trails for 21 CFR Part 11 compliance, the security edition of the software is now compatible with all of Bio-Rad’s CFX real-time PCR detection systems, including the CFX96 Touch™ and CFX384 Touch™ systems.
For more information on Bio-Rad’s CFX Manager software, please visit www.bio-rad.com/CFX-Manager3.1.